Industrial and municipal wastewater treatment has the potential of providing considerable quantities of freshwater for different purposes. Prior to its usage, heavy metal ions elimination from treated wastewater must be ensured to evade their toxic and severe impacts on the water ecosystem and humans. For this purpose, graphene oxide (GO)/manganese oxide (MnO2) nanocomposite was prepared in this study and used for adsorption of toxic metal ions from wastewater. This material was characterized using SEM, EDX, TGA, and FT-IR, among others, and their potential in toxic metal ions adsorption was evaluated. The new nanocomposite showed the presence of a high density negatively charged functional groups/active sites. This has the potential to enhance the adsorption of various metal ions and thus, their practical application in wastewater treatment. © 2022, The Author(s), under exclusive license to Springer Nature Switzerland AG.